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High frequency of inactivating mutations in the neurofibromatosis type 2 gene (NF2) in primary malignant mesotheliomas.

Malignant mesotheliomas (MMs) are aggressive tumors that develop most frequently in the pleura of patients exposed to asbestos. In contrast to many other cancers, relatively few molecular alterations have been described in MMs. The most frequent numerical cytogenetic abnormality in MMs is loss of ch...

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Publikašuvnnas:Proc Natl Acad Sci U S A
Váldodahkkit: Bianchi, A B, Mitsunaga, S I, Cheng, J Q, Klein, W M, Jhanwar, S C, Seizinger, B, Kley, N, Klein-Szanto, A J, Testa, J R
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: National Academy of Sciences 1995
Fáttát:
Liŋkkat:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC40529/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7479897/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.24.10854
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