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High frequency of inactivating mutations in the neurofibromatosis type 2 gene (NF2) in primary malignant mesotheliomas.

Malignant mesotheliomas (MMs) are aggressive tumors that develop most frequently in the pleura of patients exposed to asbestos. In contrast to many other cancers, relatively few molecular alterations have been described in MMs. The most frequent numerical cytogenetic abnormality in MMs is loss of ch...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Bianchi, A B, Mitsunaga, S I, Cheng, J Q, Klein, W M, Jhanwar, S C, Seizinger, B, Kley, N, Klein-Szanto, A J, Testa, J R
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1995
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC40529/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7479897/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.24.10854
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