Sequence and Apoptotic Activity of VacA Cytotoxin Cloned from a Helicobacter pylori Thai Clinical Isolate

The vacuolating cytotoxin VacA produced by Helicobacter pylori induces the formation of large cytoplasmic vacuoles in host gastric epithelial cells as well as a release of cytochrome C from mitochondria resulting in cell apoptosis. Considerable sequence diversity in VacA relating to different degree...

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Autori principali: Junaid, Muhammad, Al-Gubare, Sarbast, Yousef, Muhammad, Na Ubol, Mathukorn, Leetachewa, Somphob, Muanprasat, Chatchai, Angsuthanasombat, Chanan, Chaicumpa, Wanpen, Ali, Niaz, Katzenmeier, Gerd
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi Publishing Corporation 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4052787/
https://ncbi.nlm.nih.gov/pubmed/24963483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/398350
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