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Gene Modification of Mesenchymal Stem Cells and Articular Chondrocytes to Enhance Chondrogenesis

Current cell based treatment for articular cartilage and osteochondral defects are hampered by issues such as cellular dedifferentiation and hypertrophy of the resident or transplanted cells. The reduced expression of chondrogenic signalling molecules and transcription factors is a major contributin...

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Detalles Bibliográficos
Main Authors: Gurusinghe, Saliya, Strappe, Padraig
Formato: Artigo
Idioma:Inglês
Publicado: Hindawi Publishing Corporation 2014
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4052490/
https://ncbi.nlm.nih.gov/pubmed/24963479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/369528
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