The Beneficial Effects of Valproic Acid in Thyroid Cancer Are Mediated through Promoting Redifferentiation and Reducing Stemness Level: An In Vitro Study

Valproic acid (VPA) has been identified as a histone deacetylase inhibitor, inducing differentiation in transformed cells. However, no study has shown the effect of VPA in the redifferentiation induction and stemness of anaplastic thyroid. The main objective of this study was to evaluate the efficac...

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Główni autorzy: Haghpanah, Vahid, Malehmir, Mohsen, Larijani, Bagher, Ahmadian, Shahin, Alimoghaddam, Kamran, Heshmat, Ramin, Ghavamzadeh, Ardeshir, Adabi, Khadijeh, Ghaffari, Seyed H.
Format: Artigo
Język:Inglês
Wydane: Hindawi Publishing Corporation 2014
Hasła przedmiotowe:
Research Article
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4052487/
https://ncbi.nlm.nih.gov/pubmed/24963441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/218763
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