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A Comparative Cytotoxic Evaluation of Disulfiram Encapsulated PLGA Nanoparticles on MCF-7 Cells

Background: Disulfiram is oral aldehyde dehydrogenase (ALDH) inhibitor that has been used in the treatment of alcoholism. Recent studies show that this drug has anticancer properties; however, its rapid degradation has limited its clinical application. Encapsulation of disulfiram polymeric nanoparti...

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Detalhes bibliográficos
Publicado no:Int J Hematol Oncol Stem Cell Res
Main Authors: Fasehee, Hamidreza, Ghavamzadeh, Ardeshir, Alimoghaddam, Kamran, Ghaffari, Seyed-Hamidollah, Faghihi, Shahab
Formato: Artigo
Idioma:Inglês
Publicado em: Tehran University of Medical Sciences, Hematology-Oncology and Stem Cell Transplantation Research Center 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5575722/
https://ncbi.nlm.nih.gov/pubmed/28875004
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