Ubiquitin ligase Cbl-b represses IGF-I-induced epithelial mesenchymal transition via ZEB2 and microRNA-200c regulation in gastric cancer cells

BACKGROUND: Insulin-like growth factor I (IGF-I) can induce epithelial mesenchymal transition (EMT) in many epithelial tumors; however, the molecular mechanism by which this occurs is not clearly understood. Additionally, little is known about the involvement of IGF-I in gastric cancer. METHODS: Two...

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Bibliografske podrobnosti
Main Authors: Li, Heming, Xu, Ling, Li, Ce, Zhao, Lei, Ma, Yanju, Zheng, Huachuan, Li, Zhi, Zhang, Ye, Wang, Ruoyu, Liu, Yunpeng, Qu, Xiujuan
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2014
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4052283/
https://ncbi.nlm.nih.gov/pubmed/24885194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-136
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