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The adenosine system modulates Toll-like receptor function: basic mechanisms, clinical correlates and translational opportunities

Adenosine is an endogenous purine metabolite whose concentration in human blood plasma rises from nanomolar to micromolar during stress or hypoxia. Leukocytes express seven-transmembrane adenosine receptors whose engagement modulates Toll-like receptor-mediated cytokine responses, in part via modula...

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Bibliografiske detaljer
Main Authors: Coombs, Melanie R. Power, Belderbos, Mirjam E., Gallington, Leighanne C., Bont, Louis, Levy, Ofer
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4052217/
https://ncbi.nlm.nih.gov/pubmed/21342073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1586/eri.10.158
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