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The Basal Thermal Sensitivity of the TRPV1 Ion Channel Is Determined by PKCβII

Peripheral nociceptors are excited by the activation of membrane receptors and ion channels. The heat-sensitive TRPV1 ion channel responds to various noxious chemical and thermal stimuli, causing pain and itch. Here, we show that TRPV1 is coexpressed with PKCβII in a subset of mouse sensory neurons...

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Detalhes bibliográficos
Main Authors: Li, Lin, Hasan, Raquibul, Zhang, Xuming
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4051976/
https://ncbi.nlm.nih.gov/pubmed/24920628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0278-14.2014
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