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Astrocyte-Derived BDNF Supports Myelin Protein Synthesis after Cuprizone-Induced Demyelination

It is well established that BDNF may enhance oligodendrocyte differentiation following a demyelinating lesion, however, the endogenous sources of BDNF that may be harnessed to reverse deficits associated with such lesions are poorly defined. Here, we investigate roles of astrocytes in synthesizing a...

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Bibliographic Details
Main Authors: Fulmer, Clifton G., VonDran, Melissa W., Stillman, Althea A., Huang, Yangyang, Hempstead, Barbara L., Dreyfus, Cheryl F.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4051974/
https://ncbi.nlm.nih.gov/pubmed/24920623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4267-13.2014
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