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Levels of BDNF Impact Oligodendrocyte Lineage Cells following a Cuprizone Lesion

Previous work in culture has shown that basal forebrain (BF) oligodendrocyte (OLG) lineage cells respond to BDNF by increasing DNA synthesis and differentiation. Further, in the BF in vivo, reduced levels of BDNF as seen in BDNF(+/−) mice result in reduced numbers of NG2+ cells and deficits in myeli...

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Autors principals: VonDran, Melissa W., Singh, Harmandeep, Honeywell, Jean Z., Dreyfus, Cheryl F.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3203635/
https://ncbi.nlm.nih.gov/pubmed/21976503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.6595-10.2011
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