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TBX2 blocks myogenesis and promotes proliferation in rhabdomyosarcoma cells

Rhabdomyosarcomas (RMS) are the most frequent soft tissue sarcomas in children that share many features of developing skeletal muscle. We have discovered that a T-box family member, TBX2, is highly up regulated in tumor cells of both major RMS subtypes. TBX2 is a repressor that is often over express...

詳細記述

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書誌詳細
主要な著者: Zhu, Bo, Zhang, Meiling, Byrum, Stephanie D., Tackett, Alan J., Davie, Judith K.
フォーマット: Artigo
言語:Inglês
出版事項: 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4051830/
https://ncbi.nlm.nih.gov/pubmed/24470334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.28721
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