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TBX2 blocks myogenesis and promotes proliferation in rhabdomyosarcoma cells
Rhabdomyosarcomas (RMS) are the most frequent soft tissue sarcomas in children that share many features of developing skeletal muscle. We have discovered that a T-box family member, TBX2, is highly up regulated in tumor cells of both major RMS subtypes. TBX2 is a repressor that is often over express...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4051830/ https://ncbi.nlm.nih.gov/pubmed/24470334 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.28721 |
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