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TBX2 blocks myogenesis and promotes proliferation in rhabdomyosarcoma cells

Rhabdomyosarcomas (RMS) are the most frequent soft tissue sarcomas in children that share many features of developing skeletal muscle. We have discovered that a T-box family member, TBX2, is highly up regulated in tumor cells of both major RMS subtypes. TBX2 is a repressor that is often over express...

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Autors principals: Zhu, Bo, Zhang, Meiling, Byrum, Stephanie D., Tackett, Alan J., Davie, Judith K.
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4051830/
https://ncbi.nlm.nih.gov/pubmed/24470334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.28721
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