New High-Affinity Monoclonal Antibodies against Shiga Toxin 1 Facilitate the Detection of Hybrid Stx1/Stx2 In Vivo

BACKGROUND: Shiga toxin-producing E. coli (STEC) are a group of common and potentially deadly intestinal pathogens expressing Shiga toxin (Stx) as a primary virulence factor. Of the two types of Stx, Stx2 is responsible for more severe symptoms during infection, while Stx1 is almost identical to the...

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Main Authors: Skinner, Craig, Patfield, Stephanie, Stanker, Larry H., Fratamico, Pina, He, Xiaohua
格式: Artigo
語言:Inglês
出版: Public Library of Science 2014
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4051773/
https://ncbi.nlm.nih.gov/pubmed/24914553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0099854
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