Development of Monoclonal Antibodies and Immunoassays for Sensitive and Specific Detection of Shiga Toxin Stx2f

BACKGROUND: Shiga toxin 2 (Stx2) is a major virulence factor in gastrointestinal diseases caused by Escherichia coli. Although Stx2a (prototypical Stx2) is well-studied, all seven subtypes of Stx2 have been associated with disease in mammals. Several subtypes of Stx2, including Stx2f, are difficult...

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Bibliographic Details
Main Authors: Skinner, Craig, Patfield, Stephanie, Stanker, Larry, He, Xiaohua
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3775747/
https://ncbi.nlm.nih.gov/pubmed/24069462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0076563
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