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The Effect of Macromolecular Crowding on the Electrostatic Component of Barnase–Barstar Binding: A Computational, Implicit Solvent-Based Study

Macromolecular crowding within the cell can impact both protein folding and binding. Earlier models of cellular crowding focused on the excluded volume, entropic effect of crowding agents, which generally favors compact protein states. Recently, other effects of crowding have been explored, includin...

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Autori principali: Qi, Helena W., Nakka, Priyanka, Chen, Connie, Radhakrishnan, Mala L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4051634/
https://ncbi.nlm.nih.gov/pubmed/24915485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098618
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