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How Optimal Are the Binding Energetics of Barnase and Barstar?

The extracellular ribonuclease barnase and its intracellular inhibitor barstar bind fast and with high affinity. Although extensive experimental and theoretical studies have been carried out on this system, it is unclear what the relative importance of different contributions to the high affinity is...

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Detalhes bibliográficos
Main Authors: Wang, Ting, Tomic, Sanja, Gabdoulline, Razif R., Wade, Rebecca C.
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1304567/
https://ncbi.nlm.nih.gov/pubmed/15345541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.040964
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