High plasma exposure to pemetrexed leads to severe hyponatremia in patients with advanced non small cell lung cancer receiving pemetrexed-platinum doublet chemotherapy

BACKGROUND: Pemetrexed-platinum doublet therapy is a standard treatment for stage IIIb/IV nonsquamous non small cell lung cancer (NSCLC). While the regimen is associated with several grade ≥3 toxicities, hyponatremia is not a commonly reported adverse effect. Here we report an unusually high inciden...

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Autori principali: Gota, Vikram, Kavathiya, Krunal, Doshi, Kartik, Gurjar, Murari, Damodaran, Solai E, Noronha, Vanita, Joshi, Amit, Prabhash, Kumar
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove Medical Press 2014
Soggetti:
Rapid Communication
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4051622/
https://ncbi.nlm.nih.gov/pubmed/24940080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S60177
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