Elevated levels of FOXA1 facilitate androgen receptor chromatin binding resulting in a CRPC-like phenotype

Castration-resistant prostate cancer (CRPC) continues to pose a significant clinical challenge with new generation second line hormonal therapies affording limited improvement in disease outcome. As the androgen receptor (AR) remains a critical driver in CRPC, understanding the determinants of its t...

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Main Authors: Robinson, Jessica L.L., Hickey, Theresa E., Warren, Anne Y., Vowler, Sarah L., Carroll, Tom, Lamb, Alastair D., Papoutsoglou, Nikolaos, Neal, David E., Tilley, Wayne D., Carroll, Jason S.
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4051595/
https://ncbi.nlm.nih.gov/pubmed/24292680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2013.508
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