Dual role of FoxA1 in androgen receptor binding to chromatin, androgen signalling and prostate cancer

High androgen receptor (AR) level in primary tumour predicts increased prostate cancer-specific mortality. However, the mechanisms that regulate AR function in prostate cancer are poorly known. We report here a new paradigm for the forkhead protein FoxA1 action in androgen signalling. Besides pionee...

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Detalhes bibliográficos
Main Authors: Sahu, Biswajyoti, Laakso, Marko, Ovaska, Kristian, Mirtti, Tuomas, Lundin, Johan, Rannikko, Antti, Sankila, Anna, Turunen, Juha-Pekka, Lundin, Mikael, Konsti, Juho, Vesterinen, Tiina, Nordling, Stig, Kallioniemi, Olli, Hautaniemi, Sampsa, Jänne, Olli A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3209787/
https://ncbi.nlm.nih.gov/pubmed/21915096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.328
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