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Adenosine Prevents TNFα-Induced Decrease in Endothelial Mitochondrial Mass via Activation of eNOS-PGC-1α Regulatory Axis

We tested whether adenosine, a cytoprotective mediator and trigger of preconditioning, could protect endothelial cells from inflammation-induced deficits in mitochondrial biogenesis and function. We examined this question using human microvascular endothelial cells exposed to TNFα. TNFα produced tim...

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Bibliografski detalji
Glavni autori: Kalogeris, Theodore J., Baines, Christopher, Korthuis, Ronald J.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4051583/
https://ncbi.nlm.nih.gov/pubmed/24914683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098459
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