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Protein expression, characterization, crystallization and preliminary X-ray crystallographic analysis of a Fic protein from Clostridium difficile

Fic domains in proteins are found in abundance in nature from the simplest prokaryotes to animals. Interestingly, Fic domains found in two virulence factors of Gram-negative bacteria have recently been demonstrated to catalyse the transfer of the AMP moiety from ATP to small host GTPases. This post-...

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Detalhes bibliográficos
Main Authors: Welner, Ditte, Dedic, Emil, van Leeuwen, Hans C., Kuijper, Ed, Bjerrum, Morten Jannik, Østergaard, Ole, Jørgensen, René
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4051547/
https://ncbi.nlm.nih.gov/pubmed/24915103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X1400987X
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