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Structural elucidation of the hormonal inhibition mechanism of the bile acid cholate on human carbonic anhydrase II
The carbonic anhydrases (CAs) are a family of mostly zinc metalloenzymes that catalyze the reversible hydration/dehydration of CO(2) into bicarbonate and a proton. Human isoform CA II (HCA II) is abundant in the surface epithelial cells of the gastric mucosa, where it serves an important role in cyt...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
International Union of Crystallography
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4051509/ https://ncbi.nlm.nih.gov/pubmed/24914985 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1399004714007457 |
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