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Structural elucidation of the hormonal inhibition mechanism of the bile acid cholate on human carbonic anhydrase II

The carbonic anhydrases (CAs) are a family of mostly zinc metalloenzymes that catalyze the reversible hydration/dehydration of CO(2) into bicarbonate and a proton. Human isoform CA II (HCA II) is abundant in the surface epithelial cells of the gastric mucosa, where it serves an important role in cyt...

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Bibliografski detalji
Glavni autori: Boone, Christopher D., Tu, Chingkuang, McKenna, Robert
Format: Artigo
Jezik:Inglês
Izdano: International Union of Crystallography 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4051509/
https://ncbi.nlm.nih.gov/pubmed/24914985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1399004714007457
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