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Ceramide inhibits connective tissue growth factor expression by human retinal pigment epithelial cells

Connective tissue growth factor (CTGF) is known to be involved in retinal fibrotic disorders. We used human retinal pigment epithelial cells (HRPE), which play critical roles in retinal fibrosis, to examine the expression of CTGF and its regulation by ceramide and TGF-β. Real-time PCR analysis showe...

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Bibliografske podrobnosti
Main Authors: Sonoda, Shozo, Nagineni, Chandrasekharam N., Kitamura, Mizuki, Spee, Christine, Kannan, Ram, Hinton, David R.
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4051296/
https://ncbi.nlm.nih.gov/pubmed/24758915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cyto.2014.03.011
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