Differential effects of RUNX2 on the androgen receptor in prostate cancer: synergistic stimulation of a gene set exemplified by SNAI2 and subsequent invasiveness

Changes in androgen signaling during prostate carcinogenesis are associated with both inhibition of cellular differentiation and promotion of malignant phenotypes. The androgen receptor (AR)-binding transcription factor (TF) RUNX2 has been linked to prostate cancer (PCa) progression but the underlyi...

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Bibliographic Details
Main Authors: Little, Gillian H., Baniwal, Sanjeev K., Adisetiyo, Helty, Groshen, Susan, Chimge, Nyam-Osor, Kim, Sun Young, Khalid, Omar, Hawes, Debra, Jones, Jeremy O., Pinski, Jacek, Schones, Dustin E., Frenkel, Baruch
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4051204/
https://ncbi.nlm.nih.gov/pubmed/24648349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-2003
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