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Pemetrexed alters folate phenotype and inflammatory profile in EA.hy 926 cells grown under low-folate conditions
Elevated homocysteine is a risk marker for several major human pathologies. Emerging evidence suggests that perturbations of folate/homocysteine metabolism can directly modify production of inflammatory mediators. Pemetrexed acts by inhibiting thymidylate synthetase (TYMS), dihydrofolate reductase (...
Tallennettuna:
| Päätekijät: | , , , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2012
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4051202/ https://ncbi.nlm.nih.gov/pubmed/22975265 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2012.08.008 |
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