Airway Basal Cells of Healthy Smokers Express an Embryonic Stem Cell Signature Relevant to Lung Cancer

Activation of the human embryonic stem cell (hESC)-signature genes has been observed in various epithelial cancers. In this study, we found that the hESC signature is selectively induced in the airway basal stem/progenitor cell population of healthy smokers (BC-S), with a pattern similar to that act...

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Hlavní autoři: Shaykhiev, Renat, Wang, Rui, Zwick, Rachel K., Hackett, Neil R., Leung, Roland, Moore, Malcolm A. S., Sima, Camelia S., Chao, IonWa, Downey, Robert J., Strulovici-Barel, Yael, Salit, Jacqueline, Crystal, Ronald G.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4051142/
https://ncbi.nlm.nih.gov/pubmed/23857717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1459
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