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Wild-type RAS: keeping mutant RAS in CHK
Mutant RAS-driven tumorigenesis was thought for decades to arise independently of wild-type RAS isoforms, but recent evidence points to their involvement. In this issue of Cancer Cell, Grabocka et al. report how loss of wild-type RAS alters oncogenic signaling and dampens the DNA-damage response, th...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4050974/ https://ncbi.nlm.nih.gov/pubmed/24525230 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2014.01.029 |
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