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Complex environment experience rescues impaired neurogenesis, enhances synaptic plasticity, and attenuates neuropathology in familial Alzheimer’s disease-linked APPswe/PS1ΔE9 mice

Experience in complex environments induces numerous forms of brain plasticity, improving structure and function. It has been long debated whether brain plasticity can be induced under neuropathological conditions, such as Alzheimer’s disease (AD), to an extent that would reduce neuropathology, rescu...

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Detalhes bibliográficos
Main Authors: Hu, Yuan-Shih, Xu, Peng, Pigino, Gustavo, Brady, Scott T., Larson, John, Lazarov, Orly
Formato: Artigo
Idioma:Inglês
Publicado em: The Federation of American Societies for Experimental Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4050966/
https://ncbi.nlm.nih.gov/pubmed/20086049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.09-136945
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