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Complex environment experience rescues impaired neurogenesis, enhances synaptic plasticity, and attenuates neuropathology in familial Alzheimer’s disease-linked APPswe/PS1ΔE9 mice

Experience in complex environments induces numerous forms of brain plasticity, improving structure and function. It has been long debated whether brain plasticity can be induced under neuropathological conditions, such as Alzheimer’s disease (AD), to an extent that would reduce neuropathology, rescu...

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Bibliografiske detaljer
Main Authors: Hu, Yuan-Shih, Xu, Peng, Pigino, Gustavo, Brady, Scott T., Larson, John, Lazarov, Orly
Format: Artigo
Sprog:Inglês
Udgivet: The Federation of American Societies for Experimental Biology 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4050966/
https://ncbi.nlm.nih.gov/pubmed/20086049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.09-136945
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