Development of a Sensitive LC/MS/MS Method for Vitamin D Metabolites: 1,25 Dihydroxyvitamin D(2&3) Measurement Using a Novel Derivatization Agent

Active vitamin D metabolites 1,25-dihydroxyvitamin D(2) [1,25-(OH)(2)-D(2); derived from ergocalciferol] and D(3) [1,25-(OH)(2)-D(3); derived from cholecalciferol] are found in low levels in the circulation and require a very sensitive method for measurement. Radioimmunoassay (RIA) has been the meth...

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Detalhes bibliográficos
Main Authors: Hedman, Curtis J., Wiebe, Donald A., Dey, Subhakar, Plath, Josh, Kemnitz, Joseph W., Ziegler, Toni E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4050665/
https://ncbi.nlm.nih.gov/pubmed/24576767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2014.01.045
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