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Activity of D-amino acid oxidase is widespread in the human central nervous system
It has been proposed that D-amino acid oxidase (DAO) plays an essential role in degrading D-serine, an endogenous coagonist of N-methyl-D-aspartate (NMDA) glutamate receptors. DAO shows genetic association with amyotrophic lateral sclerosis (ALS) and schizophrenia, in whose pathophysiology aberrant...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4050652/ https://ncbi.nlm.nih.gov/pubmed/24959138 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnsyn.2014.00014 |
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