Mechanism for neutralizing activity by the anti-CMV gH/gL monoclonal antibody MSL-109

Cytomegalovirus (CMV) is a widespread opportunistic pathogen that causes birth defects when transmitted transplacentally and severe systemic illness in immunocompromised individuals. MSL-109, a human monoclonal IgG isolated from a CMV seropositive individual, binds to the essential CMV entry glycopr...

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Main Authors: Fouts, Ashley E., Comps-Agrar, Laëtitia, Stengel, Katharina F., Ellerman, Diego, Schoeffler, Allyn J., Warming, Søren, Eaton, Dan L., Feierbach, Becket
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2014
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4050585/
https://ncbi.nlm.nih.gov/pubmed/24843144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1404653111
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