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Inferring fitness landscapes by regression produces biased estimates of epistasis
The genotype–fitness map plays a fundamental role in shaping the dynamics of evolution. However, it is difficult to directly measure a fitness landscape in practice, because the number of possible genotypes is astronomical. One approach is to sample as many genotypes as possible, measure their fitne...
Gorde:
| Egile Nagusiak: | , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
National Academy of Sciences
2014
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4050575/ https://ncbi.nlm.nih.gov/pubmed/24843135 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1400849111 |
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