3D In Vitro Model of a Functional Epidermal Permeability Barrier from Human Embryonic Stem Cells and Induced Pluripotent Stem Cells

Cornification and epidermal barrier defects are associated with a number of clinically diverse skin disorders. However, a suitable in vitro model for studying normal barrier function and barrier defects is still lacking. Here, we demonstrate the generation of human epidermal equivalents (HEEs) from...

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Main Authors: Petrova, Anastasia, Celli, Anna, Jacquet, Laureen, Dafou, Dimitra, Crumrine, Debra, Hupe, Melanie, Arno, Matthew, Hobbs, Carl, Cvoro, Aleksandra, Karagiannis, Panagiotis, Devito, Liani, Sun, Richard, Adame, Lillian C., Vaughan, Robert, McGrath, John A., Mauro, Theodora M., Ilic, Dusko
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4050479/
https://ncbi.nlm.nih.gov/pubmed/24936454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2014.03.009
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