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Inhibition of Phosphodiesterase-1 Attenuates Cold-Induced Pulmonary Hypertension (CIPH)

Chronic exposure to cold caused pulmonary arterial hypertension (CIPH) and increased phosphodiesterase-1C (PDE-1C) expression in pulmonary arteries (PAs) in rats. The purpose of this study is to investigate a hypothesis that inhibition of PDE-1 would decrease inflammatory infiltrates and superoxide...

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Hlavní autoři: Crosswhite, Patrick, Sun, Zhongjie
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4050371/
https://ncbi.nlm.nih.gov/pubmed/23319544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.111.00676
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