FOXN1(GFP/w) Reporter hESCs Enable Identification of Integrin-β4, HLA-DR, and EpCAM as Markers of Human PSC-Derived FOXN1(+) Thymic Epithelial Progenitors

Thymic epithelial cells (TECs) play a critical role in T cell maturation and tolerance induction. The generation of TECs from in vitro differentiation of human pluripotent stem cells (PSCs) provides a platform on which to study the mechanisms of this interaction and has implications for immune recon...

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Detalhes bibliográficos
Main Authors: Soh, Chew-Li, Giudice, Antonietta, Jenny, Robert A., Elliott, David A., Hatzistavrou, Tanya, Micallef, Suzanne J., Kianizad, Korosh, Seach, Natalie, Zúñiga-Pflücker, Juan Carlos, Chidgey, Ann P., Trounson, Alan, Nilsson, Susan K., Haylock, David N., Boyd, Richard L., Elefanty, Andrew G., Stanley, Edouard G.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4050347/
https://ncbi.nlm.nih.gov/pubmed/24936476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2014.04.009
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