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Panaxadiol and Panaxatriol Derivatives as Anti-Hepatitis B Virus Inhibitors
ABSTRACT: 28 Derivatives of panaxadiol (PD) and panaxatriol were synthesized and evaluated for their anti-HBV activity on HepG 2.2.15 cells, of which 17 derivatives inhibited HBV DNA replication. Compounds 4, 9, 10, 14, and 15 showed moderate activity against HBV DNA replication with IC(50) values r...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Berlin Heidelberg
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4050313/ https://ncbi.nlm.nih.gov/pubmed/24955298 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13659-014-0018-2 |
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