Microglia is a key player in the reduction of stroke damage promoted by the new antithrombotic agent ticagrelor

The ADP-responsive P2Y(12) receptor is expressed on both platelets and microglia. Clinical data show that ticagrelor, a direct-acting, reversibly binding P2Y(12)-receptor antagonist, reduces total cardiovascular events, including stroke. In our present study, we investigated the expression of P2Y(12...

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Autori principali: Gelosa, Paolo, Lecca, Davide, Fumagalli, Marta, Wypych, Dorota, Pignieri, Alice, Cimino, Mauro, Verderio, Claudia, Enerbäck, Malin, Nikookhesal, Elham, Tremoli, Elena, Abbracchio, Maria P, Sironi, Luigi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2014
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4050242/
https://ncbi.nlm.nih.gov/pubmed/24643079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2014.45
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