The orphan receptor GPR17 identified as a new dual uracil nucleotides/cysteinyl-leukotrienes receptor

Nucleotides and cysteinyl-leukotrienes (CysLTs) are unrelated signaling molecules inducing multiple effects through separate G-protein-coupled receptors: the P2Y and the CysLT receptors. Here we show that GPR17, a Gi-coupled orphan receptor at intermediate phylogenetic position between P2Y and CysLT...

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Bibliografische gegevens
Hoofdauteurs: Ciana, Paolo, Fumagalli, Marta, Trincavelli, Maria Letizia, Verderio, Claudia, Rosa, Patrizia, Lecca, Davide, Ferrario, Silvia, Parravicini, Chiara, Capra, Valérie, Gelosa, Paolo, Guerrini, Uliano, Belcredito, Silvia, Cimino, Mauro, Sironi, Luigi, Tremoli, Elena, Rovati, G Enrico, Martini, Claudia, Abbracchio, Maria P
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2006
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1589991/
https://ncbi.nlm.nih.gov/pubmed/16990797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601341
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