Staphylococcal nuclease domain containing-1 (SND1) promotes migration and invasion via angiotensin II type 1 receptor (AT1R) and TGFβ signaling

Staphylococcal nuclease domain containing-1 (SND1) is overexpressed in human hepatocellular carcinoma (HCC) patients and promotes tumorigenesis by human HCC cells. We now document that SND1 increases angiotensin II type 1 receptor (AT1R) levels by increasing AT1R mRNA stability. This results in acti...

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Hauptverfasser: Santhekadur, Prasanna K., Akiel, Maaged, Emdad, Luni, Gredler, Rachel, Srivastava, Jyoti, Rajasekaran, Devaraja, Robertson, Chadia L., Mukhopadhyay, Nitai D., Fisher, Paul B., Sarkar, Devanand
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4050181/
https://ncbi.nlm.nih.gov/pubmed/24918049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fob.2014.03.012
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