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CAR T cells for solid tumors: armed and ready to go?

CAR T cells face a unique set of challenges in the context of solid tumors. To induce a favorable clinical outcome, CAR T cells have to surmount a series of increasingly arduous tasks. First they have to be made specific for an antigen whose expression clearly demarcates tumor from normal tissue. Th...

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Библиографические подробности
Главные авторы: Kakarla, Sunitha, Gottschalk, Stephen
Формат: Artigo
Язык:Inglês
Опубликовано: 2014
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4050065/
https://ncbi.nlm.nih.gov/pubmed/24667962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PPO.0000000000000032
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