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Unrepaired DNA damage facilitates elimination of uniparental chromosomes in interspecific hybrid cells

Elimination of uniparental chromosomes occurs frequently in interspecific hybrid cells. For example, human chromosomes are always eliminated during clone formation when human cells are fused with mouse cells. However, the underlying mechanisms are still elusive. Here, we show that the elimination of...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Wang, Zheng, Yin, Hao, Lv, Lei, Feng, Yingying, Chen, Shaopeng, Liang, Junting, Huang, Yun, Jiang, Xiaohua, Jiang, Hanwei, Bukhari, Ihtisham, Wu, Lijun, Cooke, Howard J, Shi, Qinghua
التنسيق: Artigo
اللغة:Inglês
منشور في: Landes Bioscience 2014
الموضوعات:
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC4049971/
https://ncbi.nlm.nih.gov/pubmed/24608870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.28296
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