Unrepaired DNA damage facilitates elimination of uniparental chromosomes in interspecific hybrid cells

Elimination of uniparental chromosomes occurs frequently in interspecific hybrid cells. For example, human chromosomes are always eliminated during clone formation when human cells are fused with mouse cells. However, the underlying mechanisms are still elusive. Here, we show that the elimination of...

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Hlavní autoři: Wang, Zheng, Yin, Hao, Lv, Lei, Feng, Yingying, Chen, Shaopeng, Liang, Junting, Huang, Yun, Jiang, Xiaohua, Jiang, Hanwei, Bukhari, Ihtisham, Wu, Lijun, Cooke, Howard J, Shi, Qinghua
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4049971/
https://ncbi.nlm.nih.gov/pubmed/24608870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.28296
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