Unrepaired DNA damage facilitates elimination of uniparental chromosomes in interspecific hybrid cells

Elimination of uniparental chromosomes occurs frequently in interspecific hybrid cells. For example, human chromosomes are always eliminated during clone formation when human cells are fused with mouse cells. However, the underlying mechanisms are still elusive. Here, we show that the elimination of...

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Huvudupphovsmän: Wang, Zheng, Yin, Hao, Lv, Lei, Feng, Yingying, Chen, Shaopeng, Liang, Junting, Huang, Yun, Jiang, Xiaohua, Jiang, Hanwei, Bukhari, Ihtisham, Wu, Lijun, Cooke, Howard J, Shi, Qinghua
Materialtyp: Artigo
Språk:Inglês
Publicerad: Landes Bioscience 2014
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4049971/
https://ncbi.nlm.nih.gov/pubmed/24608870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.28296
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