Involvement of peroxisome proliferator-activated receptor β/δ (PPAR β/δ) in BDNF signaling during aging and in Alzheimer disease: Possible role of 4-hydroxynonenal (4-HNE)

Aging and many neurological disorders, such as AD, are linked to oxidative stress, which is considered the common effector of the cascade of degenerative events. In this phenomenon, reactive oxygen species play a fundamental role in the oxidative decomposition of polyunsaturated fatty acids, resulti...

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Huvudupphovsmän: Benedetti, Elisabetta, D’Angelo, Barbara, Cristiano, Loredana, Di Giacomo, Erica, Fanelli, Francesca, Moreno, Sandra, Cecconi, Francesco, Fidoamore, Alessia, Antonosante, Andrea, Falcone, Roberta, Ippoliti, Rodolfo, Giordano, Antonio, Cimini, Annamaria
Materialtyp: Artigo
Språk:Inglês
Publicerad: Landes Bioscience 2014
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4049970/
https://ncbi.nlm.nih.gov/pubmed/24621497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.28295
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