An automated climbing apparatus to measure chemotherapy-induced neurotoxicity in Drosophila melanogaster

We have developed a novel model system in Drosophila melanogaster to study chemotherapy-induced neurotoxicity in adult flies. Neurological deficits were measured using a manual geotactic climbing assay. The manual assay is commonly used; however, it is laborious, time-consuming, subject to human err...

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Bibliografske podrobnosti
Main Authors: Podratz, Jewel L, Staff, Nathan P, Boesche, Joshua B, Giorno, Nicholas J, Hainy, Matthew E, Herring, Shaun A, Klennert, Michael T, Milaster, Christian, Nowakowski, Steve E, Krug, II, Randall G, Peng, Ying, Windebank, Anthony J
Format: Artigo
Jezik:Inglês
Izdano: Landes Bioscience 2013
Teme:
Methods and Technical Advances
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4049852/
https://ncbi.nlm.nih.gov/pubmed/23695893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/fly.24789
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