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Drosophila melanogaster: A new model to study cisplatin-induced neurotoxicity

Platinum-based compounds are widely used and effective chemotherapeutic agents; however, sensory peripheral neuropathy is a dose-limiting and long term side effect for 20-30% of patients. A critical question is whether the mechanisms of cell death underlying clinical efficacy can be separated from t...

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Detalhes bibliográficos
Main Authors: Podratz, Jewel L., Staff, Nathan P., Froemel, Dara, Wallner, Anna, Wabnig, Florian, Bieber, Allan J., Tang, Amy, Windebank, Anthony J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3131093/
https://ncbi.nlm.nih.gov/pubmed/21514385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2011.03.022
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