Sphingosine analog fingolimod (FTY720) increases radiation sensitivity of human breast cancer cells in vitro

Radiotherapy is one of the most effective therapeutic strategies for breast cancer patients, although its efficacy may be reduced by intrinsic radiation resistance of cancer cells. Recent investigations demonstrate a link between cancer cell radio-resistance and activation of sphingosine kinase (Sph...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Marvaso, Giulia, Barone, Agnese, Amodio, Nicola, Raimondi, Lavinia, Agosti, Valter, Altomare, Emanuela, Scotti, Valerio, Lombardi, Angela, Bianco, Roberto, Bianco, Cataldo, Caraglia, Michele, Tassone, Pierfrancesco, Tagliaferri, Pierosandro
Format: Artigo
Sprache:Inglês
Veröffentlicht: Landes Bioscience 2014
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4049795/
https://ncbi.nlm.nih.gov/pubmed/24657936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.28556
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