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The emerging roles of ARID1A in tumor suppression

ARID1A has emerged as a tumor suppressor gene, which is mutated in a broad spectrum of cancers, especially in those arising from ectopic or eutopic endometrium. As a subunit of SWI/SNF chromatin remodeler, ARID1A facilitates target-specific binding of SWI/SNF complexes to chromatin, thereby altering...

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Detalhes bibliográficos
Main Authors: Wu, Ren-Chin, Wang, Tian-Li, Shih, Ie-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4049780/
https://ncbi.nlm.nih.gov/pubmed/24618703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.28411
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